Clinical commitment in Phase II Includes a continuity Clinic at the NMFF or Jesse Brown VHA site for one half-day per week if laboratory research is pursued and 2-3 half –days if a clinical research track is pursued; fellows are encouraged to link this experience to their area of chosen research. In addition fellows take periodic weekend calls.
Fellows will be encouraged and supported to attend special AACR run workshops in either Methods of Clinical Cancer Research (if in the Clinical Research Track) or Molecular Biology of Clinical Oncology. Fellows should note the due dates for these applications so they can carefully prepare their application materials with faculty guidance.
Each fellow, during their research training years, is also supported to attend one meeting per year, which may be ASH, ASCO, AACR or another meeting pertinent to their research program.
Clinical Research Track
The faculty of the Division include nationally and internationally-recognized clinical investigators known for their expertise in a various disease sites. These individuals are leaders who write the clinical practice guidelines promulgated by the National Comprehensive Cancer Network and other organizations. Members of our faculty are leaders within the Eastern Cooperative Oncology Group and other Cooperative Groups and have led pivotal clinical trials leading to changes in the way cancer medicine is practiced. Faculty members serve on the editorial boards of publications such as The Journal of the American Medical Association, Journal of Clinical Oncology, Journal of Supportive Oncology, Clinical Breast Cancer and Cancer, Oncology, Clinical Cancer Research,Epidemiology, Biomarkers and Prevention. Faculty have the insight and ability to guide the trainee in identifying the critical clinical questions affecting patients, advice the trainee in the logistical issues involved in trial design, drug procurement and procedures and policies of the institutional review board and other regulatory agencies needed to actualize a clinical trial.
Clinical Mentors and Areas of Clinical Research
Virginia Kaklamani, MD
Raymond C. Bergan, MD
Al Benson III, MD
Mark Agulnik, MD
Elizabeth Eklund, MD
Jyoti Patel, MD
Jayesh Mehta, MD
Seema Singhal, MD
Jeffrey Raizer, MD
Mark Agulnik, MD
Each fellow in the clinical research track is expected with faculty guidance to:
Develop a prospective or retrospective clinical research protocol
Pursue opportunities in advanced clinical research training, such as through the ASH-CRTI program and courses at the Northwestern University Graduate School, such as the Clinical Research and Regulatory Administration Certificate program.
Write a focused relevant review of the medical or scientific literature.
Prepare abstracts for presentation at national meetings.
Submit applications for extramural funding.
Basic Research Track
The Basic Research Program of the Division of Hematology/Oncology is robust and growing with nearly $10 million in research funding from the NIH, NCI, Department of Defense, Leukemia and Lymphoma Society and other agencies. The divisional laboratories are located in the new Lurie research building as well as in the Olson Pavilion. Laboratories throughout the Robert H. Lurie Comprehensive Cancer Center, the School of Medicine and other Schools within Northwestern University are available to trainees. Mentors within the Division include internationally known basic researchers with a proven track record of development of physician-scientists. Members of the division serve as Editors and Editorial Board Members of Journals such as Oncogene, Blood and Cancer Research.
Divisional Basic Research Mentors
Raymond C. Bergan, MD - Invasion and Metastasis, Chemoprevention, Prostate Cancer
Elizabeth A. Eklund, MD - Signaling and Gene Regulation in Leukemia
Leo Gordon, MD - Induction of Apoptosis in Lymphoma
Hidayatullah G. Munshi, MD - Molecular Basis of Invasion, Pancreatic Cancer
Steven T. Rosen, MD - Molecular Basis of Multiple Myeloma and CLL
Additional mentors include members of the Robert H. Lurie Comprehensive Cancer Center and particularly participants in the NCI funded Oncology Training Program in Clinical Oncology Research. The Clinical Oncology Research Training Program (Steven T. Rosen, Program Leader, Robin Leikin, PhD- Administrative Director) of the Cancer Center enables four postdoctoral fellows per year to receive state-of-the-art training from mentors in five areas:
- Cancer Biology
- Viral Oncogenesis
- Tumor Invasion, Metastasis and Angiogenesis
- Hormones and Signal Transduction In Cancer
- Cancer Genes and Molecular Regulation
Each fellow in the basic research track is expected with faculty mentorship to:
- Develop an independent laboratory research project
- If needed for furthering goals of research project, attend graduate courses in the Integrated Graduate Program of The Feinberg School of Medicine in Molecular and Cancer Biology
- Publish research in peer-reviewed scientific journals
- Prepare abstracts for presentation at national meetings
- Submit applications for extramural funding
- Participate in weekly seminar series in cancer biology, including a yearly presentation of their own work