Mary F. Mulcahy, MD
Assistant Professor of Medicine
m-mulcahy@northwestern.edu

During her fellowship at Northwestern, Dr. Mulcahy worked on the role of caspases in cell death, in the lab of Vincent Cryns, MD, who developed a novel strategy for identifying targets of the caspase family of proteases essential for cell death. The goal of her research was to show that one such target protein, known to be essential for normal RNA polymerase dependent transcription elongation, is cleaved in vitro by caspases. She proposed that cell death occurs as a result, and that over expression of this protein may be implicated in cell death inhibition and oncogenesis.

Clinically her interests are in gastrointestinal cancers, including colon, esophageal, gastric (stomach), pancreatic, rectal and hepatocellular disease.