Program Objectives, MCRC Project 1
The objectives of this program are:
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Research: Inform development of interventions that will modify disease course in knee OA by delaying cartilage loss and other aspects of disease progression and to inform strategies to prevent poor function outcome and disability in persons with knee OA
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Training: Train, mentor, nurture, and advise new and early-stage investigators and provide enrichment and growth opportunities for more established investigators
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Collaborative Networks: Develop, maintain, and refine on an ongoing basis collaborative networks of scientists for faster advancement toward research and training goals
This project within our ongoing MCRC heavily involves the MCRC Epidemiology Program, Risk Factors for Incident Disease, Cartilage Loss, Function Decline, and Disability in Knee Osteoarthritis. Program members and collaborators are shown in Table 1.
| Table 1. MCRC Epidemiology Program: Risk Factors for Incident Disease, Cartilage Loss, Function Decline, and Disability in Knee OA | |
| Leena Sharma MD, Program Leader | Rheumatology |
| Alison Chang DPT, MS | Physical Therapy and Human Movement Sciences |
| Joan Chmiel PhD | Preventive Medicine |
| Carmelita Colbert MD | Rheumatology |
| Dorothy Dunlop PhD | IHS, Preventive Medicine, Rheumatology |
| Steven Gard PhD | Biomedical Engineering, Physical Medicine and Rehabilitation |
| Karen Hayes PhD | Physical Therapy and Human Movement Sciences |
| Mary McDermott MD | Preventive Medicine, General Internal Medicine |
| Kirsten Moisio PhD | Physical Therapy and Human Movement Sciences |
| Pottumarthi Prasad PhD | Radiology |
| Collaborators not at NU: Felix Eckstein MD (Paracelsus Medical University, Salzburg Austria); David Felson MD, MPH (BU); Ali Guermazi MD (BU); Michael Nevitt PhD (UCSF) | |
This project also utilizes expertise from the MCRC Translational Research Program, Joint Biomechanics and Human Movement Sciences, whose members are shown in Table 2.
| Table 2. MCRC Translational Research Program: Joint Biomechanics, Human Movement Sciences | |
| Ana Maria Acosta PhD | Physical Therapy and Human Movement Sciences |
| Alison Chang DPT, MS | Physical Therapy and Human Movement Sciences |
| Yasin Dhaher PhD | Physical Medicine and Rehabilitation |
| Steven Gard PhD | Biomedical Engineering, Physical Medicine and Rehabilitation |
| Karen Hayes PhD | Physical Therapy and Human Movement Sciences |
| Kirsten Moisio PhD | Physical Therapy and Human Movement Sciences |
| W. Zev Rymer MD, PhD | Sensorimotor Performance Program, Physiology |
| Thomas Schnitzer MD | Rheumatology, Physical Medicine and Rehabilitation |
| Leena Sharma MD | Rheumatology |
| Li-qun Zhang PhD | Physical Medicine and Rehabilitation, Orthopaedic Surgery |
