In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all accredited providers are required to mitigate and disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of accredited content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the accredited activity content over which the individual has control. Relationship information appears below.

Unlabeled and Investigational Usage:

The audience is advised that this continuing medical education activity may contain references to unlabeled uses of US Food and Drug Administration (FDA)-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

Faculty

Leonard H. Calabrese, DO (Activity Chair)

Professor of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University; R.J. Fasenmyer Chair of Clinical Immunology, Cleveland Clinic, Cleveland, Ohio

Disclosures

Disclosure: Leonard H. Calabrese, DO, has disclosed the following relevant financial relationships:
Consulting Fee: AbbVie, Amgen, Bristol-Myers Squibb, Crescendo, Genentech, Gilead, GlaxoSmithKline, Horizon, Janssen, Kiniksa, Lilly, Pfizer, Sanofi-Regeneron, UCB.
Speakers Bureau: AbbVie, Bristol-Myers Squibb, Crescendo, Genentech, Horizon, Sanofi, UCB.

Praveen Akuthota, MD

Associate Professor of Medicine, University of California San Diego, La Jolla, California

Disclosures

Disclosure: Praveen Akuthota, MD, has disclosed the following relevant financial relationships:
Royalties: UpToDate.
Consulting Fee: AstraZeneca , GlaxoSmithKline.
Contracted Research: AstraZeneca, GlaxoSmithKline.

Anisha B. Dua, MD, MPH

Associate Professor, Fellowship Program Director; Director of the Vasculitis Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois

Disclosures

Disclosure: Anisha B. Dua, MD, MPH, has disclosed the following relevant financial relationships:
Consulting Fee: AbbVie, Chemocentryx, GlaxoSmithKline, Novartis.
Speakers Bureau: AbbVie.

Michael E. Wechsler, MD, MMSc

Professor of Medicine, Director, NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, Colorado

Disclosures

Disclosure: Michael E. Wechsler, MD, MMSc, has disclosed the following relevant financial relationships:
Consulting Fee: AstraZeneca, Boehringer Ingelheim, Equillium, Genentech, GlaxoSmithKline, Novartis, Regeneron, Sanofi, Teva.
Contracted Research: AstraZeneca, Regeneron, Sanofi, Teva.

Additional Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Disclosures

Disclosure: No relevant financial relationships to disclose.

Vindico Medical Education Staff:

Disclosure: No relevant financial relationships to disclose.

Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

CME

Eosinophilic Granulomatosis With Polyangiitis (EGPA): Expert Perspectives on Diagnosis and Treatment

Authors: Leonard H. Calabrese, DO (Activity Chair); Praveen Akuthota, MD; Anisha B. Dua, MD, MPH; Michael E. Wechsler, MD, MMSc
CME Released: 6/2/2020
Valid for credit through: 6/2/2021

Start Activity

Credits Available

Physicians - maximum of 1.00 AMA PRA Category 1 Credit(s)™

You Are Eligible For
- Letter of Completion

Target Audience and Goal Statement

The intended audience for this activity is rheumatologists, pulmonologists and other health care professionals involved in the management of patients with eosinophilic granulomatosis with polyangiitis.

Eosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is a rare form of vasculitis that primarily affects the small blood vessels. Individuals diagnosed with EGPA commonly have a history of asthma and/or allergies. Inflammation associated with EGPA can lead to injury in multiple organ systems, including the sinuses, lungs, gastrointestinal system, heart, and kidneys. Early diagnosis and treatment are critical when managing EGPA to improve patient outcomes and reduce symptom burden. Education is needed to provide clinicians with the latest information regarding optimal diagnostic and management strategies, including newer steroid-sparing therapy options. In this CME activity, experts will provide guidance on differentiating EGPA from related vasculitides or eosinophilic conditions, highlight recent clinical data, and discuss therapeutic advancements.

Upon completion of this activity, participants will be able to:

Summarize current evidence regarding the immunopathology and clinical features of EGPA to aid in early diagnosis.
Recognize the burden that disease symptoms have on the quality of life of patients with EGPA.
Differentiate EGPA from other related vasculitides or eosinophilic conditions to allow for earlier treatment.
Review the use of corticosteroids and immunosuppressants in the treatment of EGPA, as well as their ability to achieve remission.
Identify patients with EGPA who may benefit from glucocorticoid-sparing options.
Incorporate evidence into practice regarding the latest clinical advances that have been shown to improve the treatment of patients with EGPA.

Disclosures

Unlabeled and Investigational Usage:

Faculty

Leonard H. Calabrese, DO (Activity Chair)

Professor of Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University; R.J. Fasenmyer Chair of Clinical Immunology, Cleveland Clinic, Cleveland, Ohio

Disclosures

Disclosure: Leonard H. Calabrese, DO, has disclosed the following relevant financial relationships:
Consulting Fee: AbbVie, Amgen, Bristol-Myers Squibb, Crescendo, Genentech, Gilead, GlaxoSmithKline, Horizon, Janssen, Kiniksa, Lilly, Pfizer, Sanofi-Regeneron, UCB.
Speakers Bureau: AbbVie, Bristol-Myers Squibb, Crescendo, Genentech, Horizon, Sanofi, UCB.

Praveen Akuthota, MD

Associate Professor of Medicine, University of California San Diego, La Jolla, California

Disclosures

Disclosure: Praveen Akuthota, MD, has disclosed the following relevant financial relationships:
Royalties: UpToDate.
Consulting Fee: AstraZeneca , GlaxoSmithKline.
Contracted Research: AstraZeneca, GlaxoSmithKline.

Anisha B. Dua, MD, MPH

Associate Professor, Fellowship Program Director; Director of the Vasculitis Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois

Disclosures

Disclosure: Anisha B. Dua, MD, MPH, has disclosed the following relevant financial relationships:
Consulting Fee: AbbVie, Chemocentryx, GlaxoSmithKline, Novartis.
Speakers Bureau: AbbVie.

Michael E. Wechsler, MD, MMSc

Professor of Medicine, Director, NJH Cohen Family Asthma Institute, Department of Medicine, National Jewish Health, Denver, Colorado

Disclosures

Disclosure: Michael E. Wechsler, MD, MMSc, has disclosed the following relevant financial relationships:
Consulting Fee: AstraZeneca, Boehringer Ingelheim, Equillium, Genentech, GlaxoSmithKline, Novartis, Regeneron, Sanofi, Teva.
Contracted Research: AstraZeneca, Regeneron, Sanofi, Teva.

Additional Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Disclosures

Disclosure: No relevant financial relationships to disclose.

Vindico Medical Education Staff:

Disclosure: No relevant financial relationships to disclose.

Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Accreditation Statements

For Physicians

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This enduring material is approved for 1 year from the date of original release, June 2, 2020 to June 1, 2021.

Contact us at: CME@VindicoCME.com

Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact CME@medscape.net

Instructions for Participation and Credit

To participate in this CME activity, you must read the objectives, answer the pretest questions, view the CME content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 80% of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate.

Follow these steps to earn CME/CE credit*:

Read the target audience, learning objectives, and author disclosures.
Study the educational content online or printed out.
Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. In addition, you must complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

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© 2020 Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2020 Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME

Eosinophilic Granulomatosis With Polyangiitis (EGPA): Expert Perspectives on Diagnosis and Treatment

Credits Available

You Are Eligible For

Target Audience and Goal Statement

Disclosures

Unlabeled and Investigational Usage:

Faculty

Leonard H. Calabrese, DO (Activity Chair)

Praveen Akuthota, MD

Anisha B. Dua, MD, MPH

Michael E. Wechsler, MD, MMSc

Additional Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Vindico Medical Education Staff:

Accreditation Statements

For Physicians

Instructions for Participation and Credit

Eosinophilic Granulomatosis With Polyangiitis (EGPA): Expert Perspectives on Diagnosis and Treatment

Educational Tool

PDF Downloads

About

Membership

Apps

WebMD Network

Editions

Faculty and Disclosures

Unlabeled and Investigational Usage:

Faculty

Leonard H. Calabrese, DO (Activity Chair)

Praveen Akuthota, MD

Anisha B. Dua, MD, MPH

Michael E. Wechsler, MD, MMSc

Additional Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Vindico Medical Education Staff:

CME

Eosinophilic Granulomatosis With Polyangiitis (EGPA): Expert Perspectives on Diagnosis and Treatment

Credits Available

You Are Eligible For

Target Audience and Goal Statement

Disclosures

Unlabeled and Investigational Usage:

Faculty

Leonard H. Calabrese, DO (Activity Chair)

Praveen Akuthota, MD

Anisha B. Dua, MD, MPH

Michael E. Wechsler, MD, MMSc

Additional Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP

Vindico Medical Education Staff:

Accreditation Statements

For Physicians

Instructions for Participation and Credit

Eosinophilic Granulomatosis With Polyangiitis (EGPA): Expert Perspectives on Diagnosis and Treatment

Educational Tool

PDF Downloads

Find Us On

About

Membership

Apps

WebMD Network

Editions