Endocrinology, Metabolism and Molecular Medicine

Epidemiological and genetic studies have shown that disruption of the circadian clock is a factor in multiple pathologies, including metabolic disease, myopathy, and cancer. Our laboratory aims to uncover the physiological impact of the circadian clock on nutrient-responsive regulatory pathways, including oxygen-sensing transcriptional networks. Indeed, we have recently identified a key connection between skeletal muscle clocks and the hypoxia-inducible factor (HIF) pathway, which drives circadian control of the hypoxic response and glucose metabolism. The goal of our laboratory is to understa...

Samuel Stupp's research is focused on self-assembly and supramolecular materials with special emphasis in regenerative medicine, organic electronics, solar energy, and cancer therapies.

My work focuses on ways to improve health and healthcare through the efficient coordination of health promotion and disease prevention activities across healthcare and community settings. I am considered a national expert in pragmatic research and natural experiments to improve the prevention and control of diabetes and other chronic conditions. My additional interests include advancing health equity, eliminating health disparities, healthcare provider interventions, quality improvement, cost effectiveness analysis, behavioral economics, and strategies for engaging community members and policy...

Nutrition and Weight Management, Medical care of the patient with overweight or obesity, Preventive medicine

genetics/genomics of complex diseases/traits; genetic epidemiology; statistical genetics; genomewide association studies; linkage; whole genome sequencing; candidate gene studies; genetic architecture of complex diseases/traits; population genetics; evolutionary genetics; signatures of selection.

Gonadal Development, Pituitary, Gonadotropins, Activin, LH, FSH

I have devoted my career to maintaining a state--of-the-art but individualized approach to primary care medicine, endocrinology, and, most specifically, the care of patients with all forms of diabetes. My main area of academic focus is to advocate for a minimization of bureaucratic obstacles that interfere with the primacy of the patient-physician relationship.

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