I have been an active clinical investigator vested in the immune-based therapy of melanoma. This has led to my role in the clinical development of initially Interleukin-2 and more recently anti-CTLA-4 and anti-PD1/PDL-1. While checkpoint therapy has been a great breakthrough in cancer treatment, additional immune-based strategies are still critically needed. Efforts to identify mechanisms of resistance to checkpoint inhibitors and approaches to overcome de novo and acquired resistance are one of my major interest. In addition I have ongoing efforts in the personalized therapy of melanoma with ...

Anti-thrombotic therapy, Atrial fibrillation, Cardiac stress testing, Cardiovascular critical care, Coronary heart disease, Ischemic heart disease, Nuclear cardiology

After practicing for 15 years in Primary Care and Internal Medicine, I obtained additional training and certification from the American Board of Obesity Medicine. My clinical focus now relates to weight management. Excess weight contributes to many disease states including type 2 diabetes, hypertension, high cholesterol, depression, anxiety, heart disease, infertility, sleep apnea and even some types of cancer. There is a recent increase in scholarly research that provides improved tools to help those struggling with weight related concerns. My practice involves the most current evidence based...

-Strain imaging in coronary heart disease -Stress echo in valvular heart disease -Patient Prosthesis mismatch. -Advanced heart failure supportive therapies

Dr. Uchida is experienced at caring for patients with complex medical illnesses. She practices evidence-based medicine which includes treating each patient as a unique individual. She also focuses on health promotion and the care of the whole person.

Judith Paice, PhD, RN is the Director of the Cancer Pain Program in the Division of Hematology-Oncology and a Research Professor of Medicine, Northwestern University; Feinberg School of Medicine. She is also a full member of the Robert H. Lurie Comprehensive Cancer Center. Dr. Paice has served as President of the American Pain Society and Secretary of the International Association for the Study of Pain. Much of Dr Paice’s clinical work has been in the relief of pain associated with cancer and HIV disease. She has traveled widely within the People’s Republic of China, Indonesia, Japan, Kenya, K...

Research in the Crispino laboratory is focused on investigating the regulatory mechanisms governing normal and malignant blood cell development, with an emphasis on understanding the growth of erythroid cells (red blood cells) and megakaryocytes (platelet-producing cells). In addition, the group has a major interest in learning how changes in normal essential regulatory molecules lead to human blood diseases, including acute leukemias and myeloproliferative neoplasms (MPNs). The lab seeks to make seminal basic science discoveries while simultaneously translating these discoveries in ways that ...

My primary research foci are in the areas of cancer survivorship, cancer pharmacoeconomics, comparative effectiveness analyses, HIV and cancer, and adverse drug reactions in older individuals living with cancer.

HIV infection, Sexually-transmitted diseases