Cardiology

Dr. Kume’s research interests focus on cardiovascular development, cardiovascular stem/progenitor cells, and angiogenesis. Current studies include the role of Foxc transcription factors in cardiovascular development and disease.

Research interests: role of mitochondria and metabolism in cardiovascular disease; cellular iron regulation. Clinical interests: general and preventive cardiology.

Major Research Interests: Molecular Basis of Organ Fibrosis: Development of Epigenetic Fibrosis Therapy. Hyperactivity of differentiated fibroblasts causes an excessive synthesis and deposition of extracellular matrix proteins in the tissues that leads to organ fibrosis, a major cause of disease-related morbidity and mortality worldwide. Fibrosis is a common end-stage pathological symptom of a wide spectrum of injury or stress related multi-organ diseases such as hypertension-induced accelerated cardiac and renal aging, myocardial infarction, liver cirrhosis, systemic sclerosis and idiopathic ...

Dr. Wilsbacher's research focuses on cardiac development and cardiomyocyte maintenance in the setting of pathological stress. Currently, the laboratory investigates the G protein-coupled receptor sphingosine-1-phosphate receptor 1 (S1Pr1) and its unexpected role in cardiomyocyte proliferation and cardiac development. Her research aims to identify the signaling mechanisms that underlie these cardiac developmental effects and to investigate whether S1Pr1 signaling contributes to cardiac remodeling in the adult heart.

Dr. Susan Kim is an associate professor of medicine. She is the Director of the Cardiac Implantable Electronic Device Clinic. She is also the Director of Cardiac Electrocardiography. Dr. Kim sees patients with heart rhythm disorders including atrial fibrillation and atrial flutter, supraventricular tachycardia, ventricular tachycardia, and bradycardia. Therapies for these rhythm disorders include watchful waiting, medication, catheter ablation, and cardiac implantable electronic devices such as pacemakers and defibrillators. Dr. Kim previously worked as a junior high school mathematics teacher...

electrocardiography, QT interval, heart rate, cardiology clinical trials

Sanjiv J. Shah, MD is the Neil Stone, MD Professor in the Division of Cardiology, Department of Medicine; Director of the T1 Center for Cardiovascular Therapeutics; and Director of the Heart Failure with Preserved Ejection Fraction Program at Northwestern University Feinberg School of Medicine. Dr. Shah’s clinical expertise and research focuses on heart failure with preserved ejection fraction (HFpEF), which is one of the most prevalent cardiovascular diseases and for which there are few proven treatments. In 2007, Dr. Shah started the first dedicated HFpEF program in the world at Northwestern...