Division of Hematology and Oncology: Department of Medicine: Feinberg School of Medicine: Northwestern University

The Division of Hematology and Oncology is focused on improving patients’ therapeutic options and quality of life while working to better prevent, diagnose and treat cancer and hematologic disorders.

“Our division houses laboratory-based investigators focused on a broad array of topics, including chemoprevention, cell signal pathways, epigenetics, immune-modulation, and nanotechnology theranostics.”

– William J. Gradishar, MD

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What We Do

Education

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Research

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Patient Care

Cancer Care

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

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Derek A Wainwright, PhD

Assistant Professor of Neurological Surgery, Medicine (Hematology and Oncology) and Microbiology-Immunology

Our laboratory utilizes DNA sequencing, gene expression profiling, proteomic analyses, flow cytometric methodology and many other basic techniques to pursue goals that are ultimately translatable for improving health and overall survival in patients with brain cancer. Although our research is primarily focused on malignant glioma, with a special emphasis on glioblastoma, we are also interested in pursuing incurable pediatric brain tumors, as well as metastatic tumors that invade the brain/spinal cord. It is our sincere hope that, the basic mechanistic investigations that we carry out, uncover ...

Elizabeth A Eklund, MD

Professor of Medicine (Hematology and Oncology)

Leukemia, Lymphoma, Myeloma

Alexander H Stegh, PhD

Associate Professor of Neurology (Neuro-oncology) and Medicine (Hematology and Oncology)

Our research program is aimed at understanding the genetic program that underlies the pathogenesis of Glioblastoma multiforme (GBM), the most prevalent and malignant form of brain cancer. Applying a combination of cell/molecular biology, oncogenomic and mouse engineering approaches, we are dedicated to systematically characterize novel gliomagenic oncogenes and tumor suppressors. We will functionally delineate and validate these pathways towards pharmaceutical opportunities using sophisticated cell culture and animal models.

Bin Zhang, MD, PhD

Professor of Medicine (Hematology and Oncology) and Microbiology-Immunology

Cancer immunology and immunotherapy. The Zhang laboratory functions as an integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment. The ongoing projects are focused on dissecting the molecular mechanisms used for tumor immune evasion based on the cutting-edge technical platforms.

Curt M Horvath, PhD

Professor of Weinberg College of Arts and Sciences, Medicine (Hematology and Oncology) and Microbiology-Immunology

Interferon, STAT

Jindan Yu, MD, PhD

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinformatics/statistical analysis to generate hypothetical concepts. We then test these hypotheses using traditional molecular or cellular biological approaches and examine the functional relevance of innovative mechanisms using in vitro cell line and in vivo mouse models. Transcription factors of particular interest to us include androgen receptor (AR), FoxA1, Polycomb group protein (EZH2), and the ...

William J Gradishar, MD

Professor of Medicine (Hematology and Oncology)

My clinical domain is breast cancer management. My clinical research interest focuses on the development of novel therapies for the treatment of breast cancer. Clinical trials focusing on precision medicine for defining the right therapy, for the right patient at the right time is our goal. To that end, molecular interogation of breast tumors are leading to novel trial design that will hopefully translate into better outcomes for our patients. In conjuction with the developmental therapeutics program, novel agents are being incorporated into clinical trials for patients with both early and ...

Robert J Lewandowski, MD

Professor of Radiology, Medicine (Hematology and Oncology) and Surgery

I am primarily interested in loco-regional therapies to treat primary and secondary liver cancers. I am involved in both pre-clinical and clinical studies along these lines. I am also very interested in the use of IVC filters in patients with venous thromboembolic disease.

Leonidas C Platanias, MD, PhD

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

chronic leukemias, multiple myeloma, non-hodgkin's lymphoma

News

Uncovering Mechanisms of Cellular Growth and Division

Solving Resistance to Emerging Cancer Immunotherapy

Study Suggests New Strategy to Treat Advanced Prostate Cancer

Pathway to Medicine: Jonathan Moreira, MD '16 GME

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Events

Lurie Cancer Center Prostate Cancer Symposium

April 10
8:00 AM - 4:00 PM

Molecular Mechanisms of Epithelial Contribution to Esophageal Inf...

April 11
1:00 PM - 2:00 PM

TEAM/SDRC Seminar: Ovarian Cancer Metastasis: Targeting the Micro...

April 12
12:00 PM - 1:00 PM

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Contact Us

We welcome your questions and comments.

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Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

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Housestaff Research Portal

Graduate Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

Visit the Housestaff Research Portal

Giving

Support What We Do

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

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Contact Terri Dillon for more information on supporting the Division of Hematology-Oncology at 312-503-4837 or terri-dillon@northwestern.edu.