Northwestern University Feinberg School of Medicine
Department of Medicine

Pulmonary and Critical Care

About Us

The Division of Pulmonary and Critical Care strives to advance our knowledge of lung health and disease through a combination of education and research.

“We have in recent years expanded our research programs, established advanced pulmonary disease subspecialty clinics and successfully opened a lung transplantation program at Northwestern.”

– Scott Budinger, MD

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Scott

What We Do

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

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Ravi Kalhan

Professor of Medicine (Pulmonary and Critical Care) and Preventive Medicine

Ravi Kalhan, MD, MS is Director of the Northwestern Asthma and Chronic Obstructive Pulmonary Disease (COPD) Program where comprehensive care is provided to patients with asthma and COPD at all stages of severity. Dr. Kalhan additionally serves as medical director of the lung volume reduction program leading the multidisciplinary evaluation of patients for both bronchoscopic and surgical approaches to severe COPD. Dr. Kalhan attended college at Brown University in Providence, RI where he majored in modern American history. He subsequently entered medical school at Case Western Reserve Universit...

Manu Jain

Professor of Medicine (Pulmonary and Critical Care) and Pediatrics

My primary research interest is in lung repair after acute injury with a focus on TGF-beta mediated signaling. We have identified mitochondrial generated reactive oxygen species as important in TGF-bête mediated gene expression and are working to identify novel therapeutic targets in this pathway. We are also interested in modulating the ubiquitin-proteosomal pathway as a therapeutic target for tissue fibrosis. I have a clinical translational interest in Cystic Fibrosis. I am the site co-PI for the CF Foundation sponsored clinical trial network, The Therapeutic Development Network. I am also i...

Colin Thomas Gillespie

Associate Professor of Medicine (Pulmonary and Critical Care) and Surgery

Dr. Gillespie's clinical interest includes the treatment of thoracic malignancies, specifically with regard to the application of novel technologies in Interventional Pulmonology to improve the diagnosis and treat thoracic malignancies with minimal invasiveness. He also has extensive experience in the bronchoscopic management of tracheal stenosis and the airway complications associated with Lung Transplantation. Dr Gillespie has advanced training in the following techniques: flexible and rigid bronchoscopy, balloon bronchoplasty, endobronchial stent placement (silicon, hybrid, and metallic), e...

Robert Goldman

Professor of Cell and Developmental Biology and Medicine (Pulmonary and Critical Care)

We study the structure, function and dynamic properties of intermediate filaments in essential mammalian cell biological phenomena. Our work focuses on the role of cytoskeletal intermediate filaments in regulating cell shape, mechanics, signal transduction, adhesion, cell motility and molecular cross talk with microtubules and microfilaments. We are also determining the roles of the nuclear lamins in regulating nuclear architecture and chromatin organization.

Marc A Sala

Assistant Professor of Medicine (Pulmonary and Critical Care)

My primary goal is to provide compassionate, evidence-based care to people with lung diseases or in the ICU. I am a board-certified pulmonologist and intensivist and have sub-specialty interests in cystic fibrosis, bronchiectasis, and lung transplant. During my fellowship, I acquired experience in laboratory science under Jing Liu, PhD, and firmly believe advancement of excellent medicine is only possible through scientific research. To that end, I spend a portion of my time committed to research of lung disease biology.

Paul Andrew Reyfman

Instructor of Medicine (Pulmonary and Critical Care)

I am an aspiring physician scientist in the Division of Pulmonary and Critical Care Medicine. I received an MD and then completed residency in internal medicine at the Columbia University College of Physicians and Surgeons. I came to Northwestern for fellowship training in pulmonary and critical care medicine, and then joined the faculty here as an instructor in 2017.

Karen M Ridge

Professor of Medicine (Pulmonary and Critical Care) and Cell and Developmental Biology

My research interests focus on the intermediate filaments (IFs), which are cytoskeletal structures that are crucial for maintaining the structural integrity of cells and tissues. In general, my lab focuses on the non-mechanical roles for the IF cytoskeleton such as how IFs regulate cell migration and cell survival, and the mechanisms by which IFs are a scaffold for stress-activated kinases and adaptor proteins. We investigated whether micromechanical forces, such as shear stress and stretch, had an effect on the keratin intermediate filament (IF) network in alveolar epithelial cells. We demons...

GR Scott Budinger

Professor of Medicine (Pulmonary and Critical Care) and Cell and Developmental Biology

Asthma; Idiopathic Pulmonary Fibrosis; Pulmonary Fibrosis; Pulmonary Thromboembolism; Sarcoidosis

Seok-Jo Kim

Research Assistant Professor of Medicine (Pulmonary and Critical Care)

Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases. - the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..). - the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.

Lisa F Wolfe

Associate Professor of Medicine (Pulmonary and Critical Care) and Neurology - Ken and Ruth Davee Department

Studying devices for ventilatory support used in home based settings. This is most relevant to those with neuromuscular disorders and sleep related breathing disorders.

Contact Pulmonary and Critical Care

We welcome your questions and comments.

Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

Learn More

Housestaff Research Portal

Graduate Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

Visit the Housestaff Research Portal

Giving

Support What We Do

Dave McCreery

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

Make an online donation

You can contact Dave McCreery for more information on supporting the Division of Pulmonary and Critical Care at 312-503-6099 or david.mccreery@northwestern.edu

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