Using mathematical modeling and optical imaging they developed themselves, a Northwestern University research team has discovered how chromatin folds at the single-cell level.

Cara J. Gottardi, PhD, has been appointed director of the Walter S. and Lucienne Driskill Graduate Program in Life Sciences.

A study published in JAMA Internal Medicine found that the percentage of Americans who received primary care — especially those who were male, younger, of minority backgrounds or who lived in the southern region of the United States — significantly decreased between 2002 and 2015.

A unified vision for health equity in Chicago was the focus of the second IPHAM Population Health Forum, where scientists and community partners presented and discussed their work in a variety of areas.

Feinberg’s new Institute for Global Health hosted its inaugural Global Health Day symposium, a day-long event that featured presentations from each of the institute’s constituent Centers, a poster session, several panels and keynote speakers.

A Northwestern Medicine study found that almost 30 percent of healthcare professionals and trainees from high-income countries have performed outside their scope of training while working or volunteering in low- and middle-income countries.

The tissue environment and chronic exercise can both influence gene expression in skeletal muscles, according to a study published in PLOS Biology.

Faculty, staff, students and trainees gathered for the ninth annual Les Turner Symposium on ALS and NeuroRepair, a one-day event highlighting the present and future of treating ALS.

Measuring atrial fibrillation through implanted devices like pacemakers can identify patients at risk for stroke, according to a recent study.

Building on years of research and collaborations promoting optimal health and well-being among seniors, Feinberg has launched the Center for Applied Health Research on Aging.

A drug originally designed to help manage diabetes may also improve quality of life for patients with heart failure, according to a recent clinical trial.

This article was originally published in the Breakthroughs Newsletter. Find more stories like this, as well as the Breakthroughs Podcast, on the Breakthroughs homepage  Cardiovascular health isn’t just about the heart, or about the thousands of veins, arteries, and capillaries that provide oxygen and other nutrients to every corner of the body. According to Clyde Yancy, MD, [...]

Genetic modifier protein Annexin A6 accelerates acute and chronic muscle injury repair by more than 50 percent.

Northwestern has established the new Center for Food Allergy and Asthma Research, which will provide investigators and patients more support while uncovering new discoveries from applied and basic science research on allergies.

Three Chicagoland high school students created the PeelTowel, a citrus peel-based, anti-microbial paper towel, and tested it in the laboratory of Alan Hauser, MD, PhD, vice chair of the Department of Microbiology-Immunology.

Total deaths from heart disease, stroke, diabetes and hypertension have been increasing since 2011, according to a new Northwestern Medicine study.

A procedure called POEM significantly improved treatment outcomes among patients with achalasia — a rare swallowing disorder — compared with a standard therapy, according to a clinical trial published in JAMA.

The Northwestern University Minority Health and Health Disparities Research Training Program, funded by the National Institutes of Health, will provide health disparities research training experiences to minority and other underrepresented students and trainees.

Sheetal Kircher, MD, ’11 GME, is laser-focused on cancer drug distribution and pricing: she spent a year as a health policy fellow at the ASCO and published a paper on the topic in JAMA.

The National Institutes of Health has awarded Northwestern University a five-year, $46 million grant to renew the Northwestern University Clinical and Translational Sciences Institute.

A new study published in JAMA found neladenoson bialanate did not improve exercise capacity among patients suffering from heart failure with preserved ejection fraction.

Daily vitamin D supplements did not significantly reduce the risk of Type 2 diabetes among adults at high risk for the disease, according to a large clinical trial published in The New England Journal of Medicine.

A targeted intervention to support asthma self-management significantly improved outcomes and medication adherence among older adults with asthma, according to a new study published in JAMA Internal Medicine.

The Louis A. Simpson and Kimberly K. Querrey Biomedical Research Center – the largest new building dedicated to biomedical research at a US medical school – has officially opened.

Low- and moderate-intensity exercise improved muscle, heart and breathing function in an animal model of Duchenne muscular dystrophy, according to a Northwestern Medicine study.

A combination of idelalisib and rituximab is an effective and safe treatment for patients with relapsed chronic lymphocytic leukemia, according to the results of a phase III clinical trial.

Mark Huffman, MD, MPH, the Quentin D. Young Professor of Health Policy, has been named a 2019 Emerging Leaders in Health and Medicine Scholar by the National Academy of Medicine.

A drug called regorafenib significantly improved progression-free survival in patients with metastatic osteosarcoma, according to a study published in the Journal of Clinical Oncology.

Feinberg graduating medical students and faculty members were recognized for their academic and teaching excellence at the seventh annual Honors Day celebration.

Students, residents, faculty and staff recently traveled to Philadelphia to attend the Student National Medical Association annual conference for current and future underrepresented minority medical students.

Death rates due to heart failure are now increasing, and this increase is most prominent among younger adults under 65, according to a new study.

Northwestern scientists have identified a new function for a transcription factor called BCL6, finding that it switches off genes involved in lipid metabolism.

A gene involved in male hormone production plays a major role in the development of polycystic ovary syndrome, according to a recent study.

Northwestern contributes to several programs that engage young learners in STEM (science, technology, engineering and math) education activities and helps them explore the many career opportunities in medicine and biomedical research.

High doses of vitamin D, in combination with chemotherapy, may improve progression-free survival in patients with advanced colorectal cancer, according to a clinical trial published in JAMA.

A delegation from the National Comprehensive Cancer Network, including Northwestern oncology leaders, recently met with health leaders in Bolivia to begin generating cancer treatment recommendations to fit the country’s unique needs.

Robert Riestenberg, a third-year medical student, was the first author of a recent study that evaluated statin use among people with HIV, a population at an increased risk for cardiovascular disease.

Northwestern scientists recently identified a new protein complex that is upregulated in acute myeloid leukemia, potentially explaining why current therapies are often ineffective.

More than 450 scientists, trainees, students and faculty presented posters and abstracts at Feinberg’s 15th Annual Lewis Landsberg Research day — the largest celebration of scientific investigation at Feinberg to date.

Feinberg investigators are conducting basic science research, epidemiological studies and drug trials of new therapies for food allergies to uncover the breadth of the problem, understand the basic cellular pathways and develop new avenues of treatment.

Measures of structural changes derived from cardiac magnetic resonance imaging (CMR) have significant potential as a noninvasive way to measure the risk of heart transplant rejection, according to a new study.

Northwestern Medicine scientists discovered how circadian rhythm regulates hunger, a long-suspected connection that was identified in a study published in Cell Metabolism

In a study published in the Journal of Experimental Medicine, Northwestern Medicine scientists identified a new therapeutic target that may help protect kidney function in patients with diabetes.

Forty new members were inducted into Northwestern’s chapter of the Alpha Omega Alpha medical honor society during a ceremony on March 12.

According to a recent study, a novel nanoparticle-based drug repaired neurons and improved microvasculature in a mouse model of spinocerebellar ataxia 1, a degenerative disease that affects the cerebellum.

Northwestern Medicine investigators discovered a method to modulate levels of a protein that is known to drive inflammation, by manipulating levels of an amino acid known as serine.

Jacob Pierce, a third-year student in Northwestern’s MD/MPH Combined Degree Program, is the first author of a study that found adverse childhood experiences significantly increase the risk for heart attack and stroke later in life.

Northwestern faculty translate cardiovascular discoveries into clinical guidelines for the nation.

Northwestern scientists came together to discuss the importance of women’s health research and mark the third anniversary of a landmark sex-inclusion policy by the NIH.

Americans with primary care received significantly more high-value care and reported better patient experience and healthcare access, compared to those without primary care, according to a study published in JAMA Internal Medicine.

A Northwestern Medicine study provides new insights into a signaling pathway in metastatic prostate cancer and suggests that a novel drug combination may improve treatment response and slow cancer growth.

A new study published in The BMJ illustrates the scale of inappropriate antibiotic prescribing in the U.S. outpatient setting, with the most comprehensive estimates to date.

Northwestern Medicine scientists have demonstrated that a specific mitochondrial protein complex is essential to the immunosuppressive activity of regulatory T-cells.

Northwestern Medicine scientists have identified a gene, called isocitrate dehydrogenase 3-alpha, that promotes tumors in grade IV glioblastoma, according to a study published in Science Advances.

In Feinberg's unique Education-Centered Medical Home program, medical students learn to provide primary care to vulnerable populations living in Chicago.

Two drugs commonly prescribed to treat Type 2 diabetes carry a high risk of cardiovascular events such as heart attack, stroke, heart failure or amputation, according to a new Northwestern Medicine study.

A drug called brentuximab vedotin combined with chemotherapy significantly improved overall survival for patients with a type of T-cell lymphoma, according to a clinical trial in The Lancet.

Northwestern Medicine scientists have discovered that an enzyme called EZH2 can activate expression of the androgen receptor gene, which drives prostate cancer growth.

Men with inflammatory bowel disease have four to five times higher risk of prostate cancer, according to a new 20-year study.

Inhibiting CHAF1B, a protein that normally helps replenish blood cells, may be a promising treatment for leukemia, according to a recent study.