CRISP Publications

1. Cao PP, Wang BF, Norton JE, Suh LA, Carter RG, Stevens WW, Staudacher AG, Huang JH, Hulse KE, Peters AT  et al.  Studies on activation and regulation of the coagulation cascade in chronic rhinosinusitis with nasal polyps.  J Allergy Clin Immunol  2022 08;150(2):467-476.e1. pii:S0091-6749(22)00286-X
2. Smith SS, Kim R, Douglas R  Is there a role for antibiotics in the treatment of chronic rhinosinusitis?  J Allergy Clin Immunol  2022 05;149(5):1504-1512. pii:S0091-6749(22)00222-6
3. Poposki JA, Klingler AI, Stevens WW, Suh LA, Tan BK, Peters AT, Abdala-Valencia H, Grammer LC, Welch KC, Smith SS  et al.  Elevation of activated neutrophils in chronic rhinosinusitis with nasal polyps.  J Allergy Clin Immunol  2022 05;149(5):1666-1674. pii:S0091-6749(21)02681-6
4. Soliai MM, Kato A, Helling BA, Stanhope CT, Norton JE, Naughton KA, Klinger AI, Thompson EE, Clay SM, Kim S  et al.  Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus.  Genome Med  2021 10 10;13(1):157. doi:10.1186/s13073-021-00967-y
5. Shintani-Smith S, Luong AU, Ramakrishnan VR, Tan BK, French DD, Kern RC  Acute invasive fungal sinusitis: Epidemiology and outcomes in the United States.  Int Forum Allergy Rhinol  2022 02;12(2):233-236. doi:10.1002/alr.22896
6. Kato A, Peters AT, Stevens WW, Schleimer RP, Tan BK, Kern RC  Endotypes of chronic rhinosinusitis: Relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches.  Allergy  2022 03;77(3):812-826. doi:10.1111/all.15074
7. Peters AT, Bose S, Guo A, Li N, Benjamin M, Prickett M, Villareal RS, Yang A, Kato A, Kern RC  et al.  Prevalence of Bronchiectasis in Patients with Chronic Rhinosinusitis in a Tertiary Care Center.  J Allergy Clin Immunol Pract  2021 08;9(8):3188-3195.e2. pii:S2213-2198(21)00560-2
8. Stevens WW, Staudacher AG, Hulse KE, Poposki JA, Kato A, Carter RG, Suh LA, Norton JE, Huang JH, Peters AT  et al.  Studies of the role of basophils in aspirin-exacerbated respiratory disease pathogenesis.  J Allergy Clin Immunol  2021 08;148(2):439-449.e5. pii:S0091-6749(21)00546-7
9. Soliai M, Sundaresan AS, Morin A, Hirsch AG, Stanhope C, Kuiper J, Schwartz BS, Ober C, Pinto JM  Two-stage genome-wide association study of chronic rhinosinusitis and disease subphenotypes highlights mucosal immunity contributing to risk.  Int Forum Allergy Rhinol  2021 04;11(4):814-817. doi:10.1002/alr.22731
10. Klingler AI, Stevens WW, Tan BK, Peters AT, Poposki JA, Grammer LC, Welch KC, Smith SS, Conley DB, Kern RC  et al.  Mechanisms and biomarkers of inflammatory endotypes in chronic rhinosinusitis without nasal polyps.  J Allergy Clin Immunol  2021 04;147(4):1306-1317. pii:S0091-6749(20)31720-6
11. McKennan C, Naughton K, Stanhope C, Kattan M, O'Connor GT, Sandel MT, Visness CM, Wood RA, Bacharier LB, Beigelman A  et al.  Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels.  Epigenetics  2021 06;16(6):662-676. doi:10.1080/15592294.2020.1817290
12. Stevens WW, Kato A  Group 2 innate lymphoid cells in nasal polyposis.  Ann Allergy Asthma Immunol  2021 02;126(2):110-117. pii:S1081-1206(20)30557-3
13. Staudacher AG, Peters AT, Carter RG, Welch KC, Stevens WW  Decreased nasal polyp eosinophils but increased mast cells in a patient with aspirin-exacerbated respiratory disease treated with reslizumab.  Ann Allergy Asthma Immunol  2020 10;125(4):490-493.e2. pii:S1081-1206(20)30476-2
14. Kuiper JR, Hirsch AG, Bandeen-Roche K, Sundaresan AS, Tan BK, Kern RC, Schleimer RP, Schwartz BS  A new approach to categorization of radiologic inflammation in chronic rhinosinusitis.  PLoS One  2020;15(6):e0235432. doi:10.1371/journal.pone.0235432
15. Takahashi T, Kato A, Suh LA, Carter RG, Stevens WW, Price CPE, Norton JE, Weibman AR, Harris KE, Peters AT  et al.  Integrin β6 microparticles in nasal lavage fluids; potential new biomarkers for basal cell activation in chronic rhinosinusitis.  Allergy  2020 12;75(12):3261-3264. doi:10.1111/all.14419
16. Ghadersohi S, Price CPE, Jensen SE, Beaumont JL, Kern RC, Conley DB, Welch KC, Peters AT, Grammer LC, Stevens WW  et al.  Development and Preliminary Validation of a New Patient-Reported Outcome Measure for Chronic Rhinosinusitis (CRS-PRO).  J Allergy Clin Immunol Pract  ;8(7):2341-2350.e1. pii:S2213-2198(20)30407-4
17. Stevens WW, Staudacher AG, Hulse KE, Carter RG, Winter DR, Abdala-Valencia H, Kato A, Suh L, Norton JE, Huang JH  et al.  Activation of the 15-lipoxygenase pathway in aspirin-exacerbated respiratory disease.  J Allergy Clin Immunol  2021 02;147(2):600-612. pii:S0091-6749(20)30627-8
18. Kwah JH, Somani SN, Stevens WW, Kern RC, Smith SS, Welch KC, Conley DB, Tan BK, Grammer LC, Yang A  et al.  Clinical factors associated with acute exacerbations of chronic rhinosinusitis.  J Allergy Clin Immunol  2020 06;145(6):1598-1605. pii:S0091-6749(20)30112-3
19. Hirsch AG, Nordberg C, Bandeen-Roche K, Tan BK, Schleimer RP, Kern RC, Sundaresan A, Pinto JM, Kennedy TL, Greene JS  et al.  Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population-based sample.  Allergy  2020 04;75(4):911-920. doi:10.1111/all.14106
20. Ogasawara N, Poposki JA, Klingler AI, Tan BK, Hulse KE, Stevens WW, Peters AT, Grammer LC, Welch KC, Smith SS  et al.  Role of RANK-L as a potential inducer of ILC2-mediated type 2 inflammation in chronic rhinosinusitis with nasal polyps.  Mucosal Immunol  2020 01;13(1):86-95. doi:10.1038/s41385-019-0215-8
21. Somani SN, Kwah JH, Yeh C, Conley DB, Grammer LC, Kern RC, Prickett M, Schleimer RP, Smith SS, Stevens WW  et al.  Prevalence and characterization of chronic rhinosinusitis in patients with non-cystic fibrosis bronchiectasis at a tertiary care center in the United States.  Int Forum Allergy Rhinol  2019 12;9(12):1424-1429. doi:10.1002/alr.22436
22. Imoto Y, Kato A, Takabayashi T, Stevens W, Norton JE, Suh LA, Carter RG, Weibman AR, Hulse KE, Harris KE  et al.  Increased thrombin-activatable fibrinolysis inhibitor levels in patients with chronic rhinosinusitis with nasal polyps.  J Allergy Clin Immunol  2019 12;144(6):1566-1574.e6. pii:S0091-6749(19)31244-8
23. Ogasawara N, Poposki JA, Klingler AI, Tan BK, Hulse KE, Stevens WW, Peters AT, Grammer LC, Welch KC, Smith SS  et al.  TNF induces production of type 2 cytokines in human group 2 innate lymphoid cells.  J Allergy Clin Immunol  2020 01;145(1):437-440.e8. pii:S0091-6749(19)31184-4
24. Kuiper JR, Hirsch AG, Bandeen-Roche K, Sundaresan AS, Tan BK, Kern RC, Schleimer RP, Schwartz BS  Workplace Indirect Cost Impacts of Nasal and Sinus Symptoms and Related Conditions.  J Occup Environ Med  2019 08;61(8):e333-e339. doi:10.1097/JOM.0000000000001636
25. Stevens WW, Peters AT, Tan BK, Klingler AI, Poposki JA, Hulse KE, Grammer LC, Welch KC, Smith SS, Conley DB  et al.  Associations Between Inflammatory Endotypes and Clinical Presentations in Chronic Rhinosinusitis.  J Allergy Clin Immunol Pract  ;7(8):2812-2820.e3. pii:S2213-2198(19)30464-7
26. Kato A  Group 2 Innate Lymphoid Cells in Airway Diseases.  Chest  2019 07;156(1):141-149. pii:S0012-3692(19)31023-2
27. Kochhar A, Zhang Y, Fisher L, Byrne P, Smith SS, Ference EH  Analysis of the operative utilization of concurrent rhinoplasty and endoscopic sinus surgery.  Laryngoscope  2020 05;130(5):E311-E319. doi:10.1002/lary.28031
28. Dilger AE, Peters AT, Wunderink RG, Tan BK, Kern RC, Conley DB, Welch KC, Holl JL, Smith SS  Procalcitonin as a Biomarker in Rhinosinusitis: A Systematic Review.  Am J Rhinol Allergy  2019 Mar;33(2):103-112. doi:10.1177/1945892418810293
29. Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M  et al.  Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.  Nat Commun  2019 02 20;10(1):880. doi:10.1038/s41467-019-08469-7
30. Kim KW, Ober C  Lessons Learned From GWAS of Asthma.  Allergy Asthma Immunol Res  2019 Mar;11(2):170-187. doi:10.4168/aair.2019.11.2.170
31. Gupta RS, Warren CM, Smith BM, Jiang J, Blumenstock JA, Davis MM, Schleimer RP, Nadeau KC  Prevalence and Severity of Food Allergies Among US Adults.  JAMA Netw Open  2019 01 04;2(1):e185630. doi:10.1001/jamanetworkopen.2018.5630
32. Khanwalkar AR, Shen J, Kern RC, Welch KC, Smith SS, Tan BK, Conley DB  Utilization of a novel interactive mobile health platform to evaluate functional outcomes and pain following septoplasty and functional endoscopic sinus surgery.  Int Forum Allergy Rhinol  2019 04;9(4):345-351. doi:10.1002/alr.22273
33. Takabayashi T, Tanaka Y, Susuki D, Yoshida K, Tomita K, Sakashita M, Imoto Y, Kato Y, Narita N, Nakayama T  et al.  Increased expression of L-plastin in nasal polyp of patients with nonsteroidal anti-inflammatory drug-exacerbated respiratory disease.  Allergy  2019 07;74(7):1307-1316. doi:10.1111/all.13677
34. Benjamin MR, Stevens WW, Li N, Bose S, Grammer LC, Kern RC, Tan BK, Conley DB, Smith SS, Welch KC  et al.  Clinical Characteristics of Patients with Chronic Rhinosinusitis without Nasal Polyps in an Academic Setting.  J Allergy Clin Immunol Pract  2019 03;7(3):1010-1016. pii:S2213-2198(18)30671-8
35. Cao PP, Wang ZC, Schleimer RP, Liu Z  Pathophysiologic mechanisms of chronic rhinosinusitis and their roles in emerging disease endotypes.  Ann Allergy Asthma Immunol  2019 01;122(1):33-40. pii:S1081-1206(18)31311-5
36. Yang HJ, LoSavio PS, Engen PA, Naqib A, Mehta A, Kota R, Khan RJ, Tobin MC, Green SJ, Schleimer RP  et al.  Association of nasal microbiome and asthma control in patients with chronic rhinosinusitis.  Clin Exp Allergy  2018 12;48(12):1744-1747. doi:10.1111/cea.13255
37. Casey JA, Wilcox HC, Hirsch AG, Pollak J, Schwartz BS  Associations of unconventional natural gas development with depression symptoms and disordered sleep in Pennsylvania.  Sci Rep  2018 07 27;8(1):11375. doi:10.1038/s41598-018-29747-2
38. Ogasawara N, Klingler AI, Tan BK, Poposki JA, Hulse KE, Stevens WW, Peters AT, Grammer LC, Welch KC, Smith SS  et al.  Epithelial activators of type 2 inflammation: Elevation of thymic stromal lymphopoietin, but not IL-25 or IL-33, in chronic rhinosinusitis with nasal polyps in Chicago, Illinois.  Allergy  2018 11;73(11):2251-2254. doi:10.1111/all.13552
39. Tan BK, Peters AT, Schleimer RP, Hulse KE  Pathogenic and protective roles of B cells and antibodies in patients with chronic rhinosinusitis.  J Allergy Clin Immunol  2018 05;141(5):1553-1560. pii:S0091-6749(18)30448-2
40. Cole M, Bandeen-Roche K, Hirsch AG, Kuiper JR, Sundaresan AS, Tan BK, Schleimer RP, Kern RC, Schwartz BS  Longitudinal evaluation of clustering of chronic sinonasal and related symptoms using exploratory factor analysis.  Allergy  2018 Aug;73(8):1715-1723. doi:10.1111/all.13470
41. Doan TC, Jeong BM, Coden ME, Loffredo LF, Bhattacharyya S, Chiarella SE, Varga J, Abdala-Valencia H, Berdnikovs S  Matrix protein tenascin-C expands and reversibly blocks maturation of murine eosinophil progenitors.  J Allergy Clin Immunol  2018 08;142(2):695-698.e4. pii:S0091-6749(18)30620-1
42. Abdala-Valencia H, Coden ME, Chiarella SE, Jacobsen EA, Bochner BS, Lee JJ, Berdnikovs S  Shaping eosinophil identity in the tissue contexts of development, homeostasis, and disease.  J Leukoc Biol  2018 07;104(1):95-108. doi:10.1002/JLB.1MR1117-442RR
43. Liu X, Hong X, Tsai HJ, Mestan KK, Shi M, Kefi A, Hao K, Chen Q, Wang G, Caruso D  et al.  Genome-wide association study of maternal genetic effects and parent-of-origin effects on food allergy.  Medicine (Baltimore)  2018 Mar;97(9):e0043. doi:10.1097/MD.0000000000010043
44. Jo A, Lee SH, Kim DY, Hong SJ, Teng MN, Kolliputi N, Lockey RF, Schleimer RP, Cho SH  Mast cell-derived plasminogen activator inhibitor type 1 promotes airway inflammation and remodeling in a murine model of asthma.  J Allergy Clin Immunol  2018 07;142(1):294-297.e5. pii:S0091-6749(18)30287-2
45. Mahdavinia M, Engen PA, LoSavio PS, Naqib A, Khan RJ, Tobin MC, Mehta A, Kota R, Preite NZ, Codispoti CD  et al.  The nasal microbiome in patients with chronic rhinosinusitis: Analyzing the effects of atopy and bacterial functional pathways in 111 patients.  J Allergy Clin Immunol  2018 07;142(1):287-290.e4. pii:S0091-6749(18)30222-7
46. Imoto Y, Kato A, Takabayashi T, Sakashita M, Norton JE, Suh LA, Carter RG, Weibman AR, Hulse KE, Stevens W  et al.  Short-chain fatty acids induce tissue plasminogen activator in airway epithelial cells via GPR41&43.  Clin Exp Allergy  2018 05;48(5):544-554. doi:10.1111/cea.13119
47. Ference EH, Suh JD, Tan BK, Smith SS  How often is sinus surgery performed for chronic rhinosinusitis with versus without nasal polyps?  Am J Rhinol Allergy  2018 Jan 01;32(1):34-39. doi:10.2500/ajra.2018.32.4495
48. Kuiper JR, Hirsch AG, Bandeen-Roche K, Sundaresan AS, Tan BK, Schleimer RP, Kern RC, Stewart WF, Schwartz BS  Prevalence, severity, and risk factors for acute exacerbations of nasal and sinus symptoms by chronic rhinosinusitis status.  Allergy  2018 Jun;73(6):1244-1253. doi:10.1111/all.13409
49. Liao B, Liu JX, Li ZY, Zhen Z, Cao PP, Yao Y, Long XB, Wang H, Wang Y, Schleimer R  et al.  Multidimensional endotypes of chronic rhinosinusitis and their association with treatment outcomes.  Allergy  2018 Jul;73(7):1459-1469. doi:10.1111/all.13411
50. John Staniorski C, Price CPE, Weibman AR, Welch KC, Conley DB, Shintani-Smith S, Stevens WW, Peters AT, Grammer L, Lidder AK  et al.  Asthma onset pattern and patient outcomes in a chronic rhinosinusitis population.  Int Forum Allergy Rhinol  2018 04;8(4):495-503. doi:10.1002/alr.22064