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Northwestern University Feinberg School of Medicine
Department of Medicine

Hematology and Oncology

About Us

The Division of Hematology and Oncology is focused on improving patients’ therapeutic options and quality of life while working to better prevent, diagnose and treat cancer and hematologic disorders.

“Our division houses laboratory-based investigators focused on a broad array of topics, including chemoprevention, cell signal pathways, epigenetics, immune-modulation, and nanotechnology theranostics.”

– William J. Gradishar, MD

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What We Do

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

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William J Gradishar

Professor of Medicine (Hematology and Oncology)

My clinical domain is breast cancer management. My clinical research interest focuses on the development of novel therapies for the treatment of breast cancer. Clinical trials focusing on precision medicine for defining the right therapy, for the right patient at the right time is our goal. To that end, molecular interogation of breast tumors are leading to novel trial design that will hopefully translate into better outcomes for our patients. In conjuction with the developmental therapeutics program, novel agents are being incorporated into clinical trials for patients with both early and lat...

Elspeth Morrison Beauchamp

Research Assistant Professor of Medicine (Hematology and Oncology)

Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.

Jane N Winter

Professor of Medicine (Hematology and Oncology)

Hodgkin's disease, Leukemia, Lymphoma

Young Kwang Chae

Associate Professor of Medicine (Hematology and Oncology)

Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway

Seema Singhal

Professor of Medicine (Hematology and Oncology)

Myeloma, Transplantation

Leo I Gordon

Professor of Medicine (Hematology and Oncology)

The overarching goal of my involvement in translational research is to improve the outcome of patients with lymphoma. With scientists in the US and abroad, we are currently investigating novel signaling pathways in lymphoma, using cell lines and animal model systems. More specifically, our research focuses on the biology of reactive oxygen species signaling pathways in lymphoma. Active investigations include: 1) the biology of the lactone diterpenoids in lymphoma; 2) the development of all trans retinoic acid (ATRA) and curcumin loaded nanodisks as a drug delivery vehicle in mantle cell lympho...

Alexander H Stegh

Associate Professor of Neurology (Neuro-oncology) and Medicine (Hematology and Oncology)

Our research program is aimed at understanding the genetic program that underlies the pathogenesis of Glioblastoma multiforme (GBM), the most prevalent and malignant form of brain cancer. Applying a combination of cell/molecular biology, oncogenomic and mouse engineering approaches, we are dedicated to systematically characterize novel gliomagenic oncogenes and tumor suppressors. We will functionally delineate and validate these pathways towards pharmaceutical opportunities using sophisticated cell culture and animal models.

Sheetal M Kircher

Associate Professor of Medicine (Hematology and Oncology)

My clinical interests include treating gastrointestinal malignancies. My research interests are on improving the quality of cancer care and better understanding the trends in use and expenditure of services and drugs. I am also interested in evaluation of cancer-related health policies.

Jeffrey A Sosman

Professor of Medicine (Hematology and Oncology)

I have been an active clinical investigator vested in the immune-based therapy of melanoma. This has led to my role in the clinical development of initially Interleukin-2 and more recently anti-CTLA-4 and anti-PD1/PDL-1. While checkpoint therapy has been a great breakthrough in cancer treatment, additional immune-based strategies are still critically needed. Efforts to identify mechanisms of resistance to checkpoint inhibitors and approaches to overcome de novo and acquired resistance are one of my major interest. In addition I have ongoing efforts in the personalized therapy of melanoma with ...

Elizabeth A Eklund

Professor of Medicine (Hematology and Oncology)

Leukemia, Lymphoma, Myeloma

Contact Us

We welcome your questions and comments.

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Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

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Housestaff Research Portal

Graduate Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

Visit the Housestaff Research Portal

Giving

Support What We Do

Terri Dillon

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

Make an online donation

Contact Terri Dillon for more information on supporting the Division of Hematology-Oncology at 312-503-4837 or terri-dillon@northwestern.edu.

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