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Hematology and Oncology

About Us

The Division of Hematology and Oncology is focused on improving patients’ therapeutic options and quality of life while working to better prevent, diagnose and treat cancer and hematologic disorders.

Our division houses laboratory-based investigators focused on a broad array of topics, including chemoprevention, cell signal pathways, epigenetics, immune-modulation, and nanotechnology theranostics.”

– William J. Gradishar, MD

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What We Do

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

Robert J Lewandowski

Professor of Radiology (Vascular and Interventional Radiology), Medicine (Hematology and Oncology) and Surgery

I am primarily interested in loco-regional therapies to treat primary and secondary liver cancers. I am involved in both pre-clinical and clinical studies along these lines. I am also very interested in the use of IVC filters in patients with venous thromboembolic disease.

Elizabeth A Eklund

Professor of Medicine (Hematology and Oncology)

Leukemia, Lymphoma, Myeloma

Elspeth Morrison Beauchamp

Research Assistant Professor of Medicine (Hematology and Oncology)

Dr. Beauchamp's research has focused on developing drugs for non-traditional targets through inhibiting protein-protein interactions in order to affect cellular function and target cancer cells. Current work is investigating novel interactors with mTORC components in order to developing novel therapeutic strategies that target the mTOR pathways in myeloid leukemias.

Marcus Ernst Peter

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

The lab of Dr. Marcus E. Peter studies various forms of cell death including apoptosis, which is a fundamental process to regulate homeostasis of all tissues and to eliminate unwanted cells specifically in the immune system. Another interest lies in the study of RNA interference and based on toxic RNAs to development a novel form of cancer treatment. The laboratory is located within the Robert H. Lurie Cancer Center at Northwestern University.

Jeffrey A Sosman

Professor of Medicine (Hematology and Oncology)

I have been an active clinical investigator vested in the immune-based therapy of melanoma. This has led to my role in the clinical development of initially Interleukin-2 and more recently anti-CTLA-4 and anti-PD1/PDL-1. While checkpoint therapy has been a great breakthrough in cancer treatment, additional immune-based strategies are still critically needed. Efforts to identify mechanisms of resistance to checkpoint inhibitors and approaches to overcome de novo and acquired resistance are one of my major interest. In addition I have ongoing efforts in the personalized therapy of melanoma with ...

Jindan Yu

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinformatics/statistical analysis to generate hypothetical concepts. We then test these hypotheses using traditional molecular or cellular biological approaches and examine the functional relevance of innovative mechanisms using in vitro cell line and in vivo mouse models. Transcription factors of particular interest to us include androgen receptor (AR), FoxA1, Polycomb group protein (EZH2), and the Ets...

Leo I Gordon

Professor of Medicine (Hematology and Oncology)

The overarching goal of my involvement in translational research is to improve the outcome of patients with lymphoma. With scientists in the US and abroad, we are currently investigating novel signaling pathways in lymphoma, using cell lines and animal model systems. More specifically, our research focuses on the biology of reactive oxygen species signaling pathways in lymphoma. Active investigations include: 1) the biology of the lactone diterpenoids in lymphoma; 2) the development of all trans retinoic acid (ATRA) and curcumin loaded nanodisks as a drug delivery vehicle in mantle cell lympho...

Panagiotis Ntziachristos

Assistant Professor of Biochemistry and Molecular Genetics and Medicine (Hematology and Oncology)

The Ntziachristos laboratory studies the mechanistic aspects of oncogenesis with an emphasis on transcriptional and epigenetic regulation of acute leukemia. Up to 25% of children with Acute Lymphoblastic Leukemia will fail frontline therapy and their prognosis is dismal. Cure rates for patients relapsing on therapy are approximate 20%. While patients with later relapses have a better prognosis, the majority eventually succumbs to the disease (overall cure rate 40 to 50%). Important questions in our laboratory are related to how oncogenes interact with each other and with epigenetic modulators ...

Kehinde U.A. Adekola

Associate Professor of Medicine (Hematology and Oncology)

Interested in stem cell/bone marrow transplantation for malignant and non-malignant disorders, and patient outcomes after these transplants. Interested in cancer health disparities specifically in hematologic disorders. Interested in global health with improvement in outcomes for hematologic and oncologic conditions in all regions.

Young Kwang Chae

Associate Professor of Medicine (Hematology and Oncology)

Personalized Cancer Therapy, Precision Medicine, Early Phase Clinical Trials, First-in-Human Study, Novel Combination Cancer Therapy, Targeted therapy, Immunotherapy, Biomarker Study, Novel Drug Development, Novel Drug Delivery System, Adaptive Clinical Trials Design, Cell Signaling Pathway, Immune Checkpoint Pathway

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We welcome your questions and comments.

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Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

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Housestaff Research Portal

Physician-Scientist Training & Resources

We offer a wide range of resources, mentorship opportunities and formal training programs to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE STARZL ACADEMY SITE

Giving

Support What We Do
Terri Dillon

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

Make an online donation

Contact Terri Dillon for more information on supporting the Division of Hematology-Oncology at 312-503-4837 or terri-dillon@northwestern.edu.