Northwestern University Feinberg School of Medicine
Department of Medicine

Hematology and Oncology

About Us

The Division of Hematology and Oncology is focused on improving patients’ therapeutic options and quality of life while working to better prevent, diagnose and treat cancer and hematologic disorders.

“Our division houses laboratory-based investigators focused on a broad array of topics, including chemoprevention, cell signal pathways, epigenetics, immune-modulation, and nanotechnology theranostics.”

– William J. Gradishar, MD

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What We Do

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

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Al B Benson

Professor of Medicine (Hematology and Oncology)

Colon cancer, Gastric cancer, Pancreas cancer, Rectal cancer

Panagiotis Ntziachristos

Assistant Professor of Biochemistry and Molecular Genetics and Medicine (Hematology and Oncology)

The Ntziachristos laboratory studies the mechanistic aspects of oncogenesis with an emphasis on transcriptional and epigenetic regulation of acute leukemia. Up to 25% of children with Acute Lymphoblastic Leukemia will fail frontline therapy and their prognosis is dismal. Cure rates for patients relapsing on therapy are approximate 20%. While patients with later relapses have a better prognosis, the majority eventually succumbs to the disease (overall cure rate 40 to 50%). Important questions in our laboratory are related to how oncogenes interact with each other and with epigenetic modulators ...

David J VanderWeele

Assistant Professor of Medicine (Hematology and Oncology)

Dr. VanderWeele did his medical and research training at the University of Chicago, where he developed a research program characterizing the heterogeneity and evolution of the cancer genome. He moved to the National Cancer Institute in Bethesda, MD, where he continued to seek to improve the treatment of prostate cancer based on patients’ specific genetic changes. He returned to Chicago in 2018 to join the GU cancer team at Northwestern University, where he continues to translate discoveries made at the bench into improved therapies in the clinic.

Jindan Yu

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

The primary research focus of the lab is to understand aberrant transcriptional and epigenetic regulation of prostate cancer. We utilize high-throughput genomic techniques in combination with bioinformatics/statistical analysis to generate hypothetical concepts. We then test these hypotheses using traditional molecular or cellular biological approaches and examine the functional relevance of innovative mechanisms using in vitro cell line and in vivo mouse models. Transcription factors of particular interest to us include androgen receptor (AR), FoxA1, Polycomb group protein (EZH2), and the Ets...

Derek A Wainwright

Assistant Professor of Neurological Surgery, Medicine (Hematology and Oncology) and Microbiology-Immunology

Our laboratory utilizes DNA sequencing, gene expression profiling, proteomic analyses, flow cytometric methodology and many other basic techniques to pursue goals that are ultimately translatable for improving health and overall survival in patients with brain cancer. Although our research is primarily focused on malignant glioma, with a special emphasis on glioblastoma, we are also interested in pursuing incurable pediatric brain tumors, as well as metastatic tumors that invade the brain/spinal cord. It is our sincere hope that, the basic mechanistic investigations that we carry out, uncover ...

Bin Zhang

Professor of Medicine (Hematology and Oncology) and Microbiology-Immunology

Cancer immunology and immunotherapy. The Zhang laboratory functions as an integrated translational research program with the goal of designing and developing new immunotherapies and immunologic strategies for cancer treatment. The ongoing projects are focused on dissecting the molecular mechanisms used for tumor immune evasion based on the cutting-edge technical platforms.

Judith A Paice

Research Professor of Medicine (Hematology and Oncology)

Judith Paice, PhD, RN is the Director of the Cancer Pain Program in the Division of Hematology-Oncology and a Research Professor of Medicine, Northwestern University; Feinberg School of Medicine. She is also a full member of the Robert H. Lurie Comprehensive Cancer Center. Dr. Paice has served as President of the American Pain Society and Secretary of the International Association for the Study of Pain. Much of Dr Paice’s clinical work has been in the relief of pain associated with cancer and HIV disease. She has traveled widely within the People’s Republic of China, Indonesia, Japan, Kenya, K...

John D Crispino

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

Research in the Crispino laboratory is focused on investigating the regulatory mechanisms governing normal and malignant blood cell development, with an emphasis on understanding the growth of erythroid cells (red blood cells) and megakaryocytes (platelet-producing cells). In addition, the group has a major interest in learning how changes in normal essential regulatory molecules lead to human blood diseases, including acute leukemias and myeloproliferative neoplasms (MPNs). The lab seeks to make seminal basic science discoveries while simultaneously translating these discoveries in ways that ...

Leonidas C Platanias

Professor of Medicine (Hematology and Oncology) and Biochemistry and Molecular Genetics

chronic leukemias, multiple myeloma, non-hodgkin's lymphoma

Barbara Pro

Professor of Medicine (Hematology and Oncology)

Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Clinical trials

Contact Us

We welcome your questions and comments.

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Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

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Housestaff Research Portal

Graduate Research Resources

We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

Visit the Housestaff Research Portal

Giving

Support What We Do

Terri Dillon

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

Make an online donation

Contact Terri Dillon for more information on supporting the Division of Hematology-Oncology at 312-503-4837 or terri-dillon@northwestern.edu.

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