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Pulmonary and Critical Care

About Us

The Division of Pulmonary and Critical Care strives to advance our knowledge of lung health and disease through a combination of education and research.

We have in recent years expanded our research programs, established advanced pulmonary disease subspecialty clinics and successfully opened a lung transplantation program at Northwestern.”

– Scott Budinger, MD

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Scott

What We Do

Faculty: Meet the Team

View individual profiles of our faculty members and learn about their research and clinical specialties.

Navdeep S Chandel

Professor of Medicine (Pulmonary and Critical Care) and Biochemistry and Molecular Genetics

Historically, reactive oxygen species (ROS) have been thought to be cellular damaging agents, lacking a physiological function. Accumulation of ROS and oxidative damage have been linked to multiple pathologies, including neurodegenerative diseases, diabetes, cancer, and premature aging. This guilt by association relationship left a picture of ROS as a necessary evil of oxidative metabolism, a product of an imperfect system. Yet few biological systems possess such flagrant imperfections, thanks to the persistent optimization of evolution, and it appears that oxidative metabolism is no different...

Manu Jain

Professor of Medicine (Pulmonary and Critical Care) and Pediatrics

My primary research interest is in lung repair after acute injury with a focus on TGF-beta mediated signaling. We have identified mitochondrial generated reactive oxygen species as important in TGF-bête mediated gene expression and are working to identify novel therapeutic targets in this pathway. We are also interested in modulating the ubiquitin-proteosomal pathway as a therapeutic target for tissue fibrosis. I have a clinical translational interest in Cystic Fibrosis. I am the site co-PI for the CF Foundation sponsored clinical trial network, The Therapeutic Development Network. I am also i...

Jane Dematte D'Amico

Professor of Medicine (Pulmonary and Critical Care)

Undergraduate studies: University of Rochester, BS 1981 Postgraduate studies: SUNY StonyBrook School of Medicine, MD 1986 Internship and Residency, SUNY StonyBrook: Internal Medicine 1986-1989 Chief Resident, SUNY StonyBrook: 1989-1990 Fellowship, Pulmonary and Critical Care Medicine, SUNY StonyBrook: 1990-1993 Northwestern University Kellogg School of Business, MBA: 2006-2008 Board Certification: Internal Medicine, Pulmonary Medicine, Critical Care Medicine

Robert Goldman

Professor of Cell and Developmental Biology and Medicine (Pulmonary and Critical Care)

We study the structure, function and dynamic properties of intermediate filaments in essential mammalian cell biological phenomena. Our work focuses on the role of cytoskeletal intermediate filaments in regulating cell shape, mechanics, signal transduction, adhesion, cell motility and molecular cross talk with microtubules and microfilaments. We are also determining the roles of the nuclear lamins in regulating nuclear architecture and chromatin organization.

Sean B Smith

Assistant Professor of Medicine (Pulmonary and Critical Care) and Surgery (Thoracic Surgery)

Bronchoscopy, EBUS, lung nodules, lung cancer, pleural disease, critical care ultrasound

Michael J Cuttica

Associate Professor of Medicine (Pulmonary and Critical Care)

I am committed to a career in patient-oriented research related to pulmonary vascular disease. Exploring the clinical impact and the mechanisms of pulmonary hypertension (PH) in patients with underlying lung disease is my primary research interest. This interest stems from my clinical experience over the last several years developing and building the Northwestern Pulmonary Hypertension Program. Pulmonary hypertension is a common complication seen in patients with lung disease, specifically chronic obstructive pulmonary disease (COPD). Although the association between the presence of PH in COPD...

Marc A Sala

Assistant Professor of Medicine (Pulmonary and Critical Care)

My primary goal is to provide compassionate, evidence-based care to people with lung diseases or in the ICU. I am a board-certified pulmonologist and intensivist and have sub-specialty interests in cystic fibrosis, bronchiectasis, and lung transplant. During my fellowship, I acquired experience in laboratory science under Jing Liu, PhD, and firmly believe advancement of excellent medicine is only possible through scientific research. To that end, I spend a portion of my time committed to research of lung disease biology.

S Marina Casalino-Matsuda

Research Associate Professor of Medicine (Pulmonary and Critical Care)

Airway inflammation in asthma and COPD. Effects of hypercapnia (elevated levels of CO2) on innate immunity and host defense in the lung. Effects of hypercapnia on airway biology.

Jacob I Sznajder

Professor of Medicine (Pulmonary and Critical Care) and Cell and Developmental Biology

Asthma, Chronic obstructive pulmonary disease (COPD), Interstitial lung disease

Rachel S Tappan

Assistant Professor of Physical Therapy and Human Movement Sciences and Medicine (Pulmonary and Critical Care)

My clinical and academic interests are in the areas of neurorehabilitation and pulmonary rehabilitation. I have practiced in clinical and research settings at the Shirley Ryan AbilityLab (formerly the Rehabilitation Institute of Chicago) for over 15 years. My clinical work has included the development of knowledge translation tools for optimal use of outcome measures in neurorehabilitation and program development for Phase II and Phase III Pulmonary Rehabilitation.

Contact Pulmonary and Critical Care

We welcome your questions and comments.

Diversity and Inclusion

The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.

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Housestaff Research Portal

Physician-Scientist Training & Resources

We offer a wide range of resources, mentorship opportunities and formal training programs to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.

VISIT THE STARZL ACADEMY SITE

Giving

Support What We Do
Dave McCreery

We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.

Make an online donation

You can contact Dave McCreery for more information on supporting the Division of Pulmonary and Critical Care at 312-503-6099 or david.mccreery@northwestern.edu