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“We have in recent years expanded our research programs, established advanced pulmonary disease subspecialty clinics and successfully opened a lung transplantation program at Northwestern.”
– Scott Budinger, MD
The Division of Pulmonary and Critical Care strives to advance our knowledge of lung health and disease through a combination of education and research.
What We Do
Faculty: Meet the Team
View individual profiles of our faculty members and learn about their research and clinical specialties.
Professor of Pediatrics (Neonatology), Cell and Molecular Biology and Medicine (Pulmonary and Critical Care)
Our lab is interested in the effects of oxygen on cell metabolism, and in the molecular mechanisms underlying cellular oxygen sensing. The signaling pathways activated by hypoxia, and their regulation of transcriptional and post-translational responses in diverse cell types are also of major interest. Current studies focus on the role of mitochondrial redox signaling in the development of pulmonary hypertension. Other current studies focus on cardiomyocyte regeneration in the heart and molecular factors that regulate hypertrophic and hyperplastic remodeling responses.
Assistant Professor of Medicine (Pulmonary and Critical Care) and Neurology - Ken and Ruth Davee Department
Home Mechanical Ventilation/Noninvasive Ventilation in Neuromuscular Disease,
Chronic Respiratory Failure,
Sleep Disorder Breathing,
Peri-operative OSA management
Associate Professor of Medicine (Pulmonary and Critical Care) and Surgery
Dr. Gillespie's clinical interest includes the treatment of thoracic malignancies, specifically with regard to the application of novel technologies in Interventional Pulmonology to improve the diagnosis and treat thoracic malignancies with minimal invasiveness. He also has extensive experience in the bronchoscopic management of tracheal stenosis and the airway complications associated with Lung Transplantation. Dr Gillespie has advanced training in the following techniques: flexible and rigid bronchoscopy, balloon bronchoplasty, endobronchial stent placement (silicon, hybrid, and metallic), ...
Associate Professor of Medicine (Pulmonary and Critical Care)
I am committed to a career in patient-oriented research related to pulmonary vascular disease. Exploring the clinical impact and the mechanisms of pulmonary hypertension (PH) in patients with underlying lung disease is my primary research interest. This interest stems from my clinical experience over the last several years developing and building the Northwestern Pulmonary Hypertension Program. Pulmonary hypertension is a common complication seen in patients with lung disease, specifically chronic obstructive pulmonary disease (COPD). Although the association between the presence of PH in COPD...
Research Assistant Professor of Medicine (Pulmonary and Critical Care)
Application of next generation sequencing technology and integrative "wet" lab approaches to basic and translational research of lung diseases, including but not limited to:
asthma, COPD, pulmonary fibrosis, acute lung injury. Understanding systemic influences on lung biology in health and disease, such as impact of central metabolism and epigenetic control of developmental checkpoints
Associate Professor of Medicine (Pulmonary and Critical Care) and Neurology - Ken and Ruth Davee Department
Studying devices for ventilatory support used in home based settings. This is most relevant to those with neuromuscular disorders and sleep related breathing disorders.
Professor of Medicine (Pulmonary and Critical Care) and Pediatrics
My primary research interest is in lung repair after acute injury with a focus on TGF-beta mediated signaling. We have identified mitochondrial generated reactive oxygen species as important in TGF-bête mediated gene expression and are working to identify novel therapeutic targets in this pathway. We are also interested in modulating the ubiquitin-proteosomal pathway as a therapeutic target for tissue fibrosis.
I have a clinical translational interest in Cystic Fibrosis. I am the site co-PI for the CF Foundation sponsored clinical trial network, The Therapeutic Development Network. I am also...
Assistant Professor of Medicine (Pulmonary and Critical Care) and Medical Education
My clinic interests include general pulmonary disease, smoking related lung disease, and smoking cessation.
Research Assistant Professor of Medicine (Pulmonary and Critical Care)
Exploring the role of mitochondrial DNA in alveolar epithelial aging and lung diseases.
- the epigenetic regulation of Klotho in cigarette smoke extract-induced lung epithelial cell DNA damage and lung diseases (e.g. lung fibrosis, COPD..).
- the role of SIRT3 in maintaining AT2 cell mtDNA by preserving mt-OGG1/ ACO-2 function important for limiting AEC mitophagy defects, apoptosis and lung fibrosis.
News
Events
Acid/Base - Keith Ferguson, MD - MICU Morning Report (Tuesdays) -...
May 14
10:00 AM - 10:30 AM
"Immunosuppression in Lung Transplant" - Rade Tomic, MD - Fellows...
May 14
12:00 PM - 1:00 PM
Lakshmi Sivarajan, MD - Pulmonary Morning Report - Pulmonary & Cr...
May 15
9:00 AM - 9:30 AM
Diversity and Inclusion
The department works toward an environment of inclusion and support through the Diversity and Cultural Affairs Council and through several dedicated events and initiatives.
Housestaff Research Portal
Graduate Research Resources
We offer a wide range of resources, mentorship opportunities and training to help our residents and fellows excel as physician-scientists. Explore all of the resources and hear from housestaff who are making research a major part of their career development plans.
Giving
Support What We Do
We invite your philanthropic partnership in helping us achieve our research and teaching missions each day.
You can contact Dave McCreery for more information on supporting the Division of Pulmonary and Critical Care at 312-503-6099 or david.mccreery@northwestern.edu